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In addition to helping out the endothelium, curcumin also reduces inflammation and oxidative damage, two factors that are also common contributors to heart disease.
Plantae (Plants) Tracheobionta (Vascular plants)Spermatophyta (Seed plants) Magnoliophyta (Flowering plants)Liliopsida (Monocotyledons) Zingiberidae Zingiberales Zingiberaceae (Ginger family) Curcuma (Curcuma)Curcuma longa (Turmeric)Certain plants manufacture chemicals that repel predators, parasites and diseases.
The anti-inflammatory effects of curcumin result from its ability to inhibit the NF-κB pathway, as well as other pro-inflammatory pathways like the mitogen-activated protein kinase (MAPK)- and the Janus kinase (JAK)/Signal transducer and activator of transcription (STAT)-dependent signaling pathways.
Inhibition of dextran sulfate sodium (DSS)-induced colitis by curcumin in mice has been associated with a downregulation of the expression of p38-MAPK and pro-inflammatory cytokine TNF-α and a reduction of myeloperoxidase (MPO) activity, a marker of neutrophil infiltration in intestinal mucosa.
Turmeric is a member of the Curcuma botanical group, which is part of the ginger family of herbs, the Zingiberaceae.
The root and rhizome stem of the Curcuma longa plant is crushed and powdered into ground Turmeric spice.
Inflammation is thought to be one of the major factors in all kinds of diseases, and turmeric contains loads of curcumin, a powerful anti-inflammatory substance.
Curcumin also helps the endothelium (the lining of blood vessels) to function at its optimum level, similar to the effect found during intense exercise.In nature's never-ending interaction between predator and prey, insects evolve the ability to digest plant toxins, while plants evolve stronger chemicals to deter their enemies.Monitoring this evolution between plants and insects represents an important field of ecological research.Researchers are also looking at curcumin for its anti-aging properties.Turmeric is safe and non-toxic and has been studied for anti-inflammatory properties, inhibiting various molecules that contribute to inflammation such as lipooxygenase, COX-2, leukotrienes, prostaglandins, nitric oxide, interferon-inducible protein, tumor necrosis factor (TNF), and interleukin-12 (IL-12).